How do you regain your health when things seem so bad?

My best friend suffers from a plethora of ailments. She is on all kinds of medication that just makes me cringe. She hates having to take it all, but doesn’t know what else to do. She takes regular pain shots; she’s on morphine for the pain too; she is also taking chemotherapy drugs; she’s even had surgeries. But she’s tried all kinds of alternative therapies too. An acupuncturist refused to do any more work on her after she had a seizure. Changes in diet didn’t alleviate the pain or symptoms. And she gets frustrated with friends and family that continually offer their unsolicited advice and assume that her pain is all in her head. I know that she is in a lot of pain and I wish I could make it all go away. I am reluctant to offer her any advice because I know that she is frustrated with her body and I know how much she has tried different things. She let’s me in on her frustrations because I don’t judge her and I don’t continually tell her what she should do. She knows that I won’t even take Tylenol for a headache. But maybe I need to be a little more active. I’m worried about her. It is easy to make steps to maintain and optimize health before things get so bad. I’m healthier now that I have been my entire life, even with my bad habits. But what do you do when your health is critical? How do you reverse decades of harmful medical intervention?